SML3598

1PBC

≥98% (HPLC)

• Synonym(s): 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
• Empirical Formula (Hill Notation): C₁₃H₆F₃N₃O
• CAS Number: 362602-12-8
• Molecular Weight: 277.20
• UNSPSC Code: 12352200
• NACRES: NA.21
• MDL number: MFCD30713081
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: -10 to -25°C
• SMILES string: OC1=CC(C(F)(F)F)=C(C#N)C2=NC3=CC=CC=C3N21

Description

Biochem/physiol Actions

1PBC is a potent and selective blocker of TMEM16A calcium-activated chloride channel that interacts with the anion pore. Also, 1PBC is a potent inhibitor of TMEM16F channel.

Potent and selective blocker of TMEM16A calcium-activated chloride channel; potent inhibitor of TMEM16F channel

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable