SML3434

Erucin

≥98% (HPLC)

• Synonym(s): (4-Isothiocyanatobutyl)(methyl)sulfane; 4-(Methylthio)butyl isothiocyanate, 1-Isothiocyanato-4-(methylthio)butane, ERU, MTBITC
• Empirical Formula (Hill Notation): C₆H₁₁NS₂
• CAS Number: 4430-36-8
• Molecular Weight: 161.29
• UNSPSC Code: 41121801
• NACRES: NA.77
• MDL number: MFCD01656048
• Assay: ≥98% (HPLC)
• Form: oil

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: oil
• color: colorless to yellow
• storage temp.: -10 to -25°C
• SMILES string: CSCCCCN=C=S
• InChI: 1S/C6H11NS2/c1-9-5-3-2-4-7-6-8/h2-5H2,1H3
• InChI key: IHQDGXUYTSZGOG-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Erucin (MTBITC) is an orally available, hydrogen sulfide (H2S)-releasing isothiocyanate (ITC) derived from glucoerucin found in the Brassicaceae family of plants (rocket salads), including arugula (Eruca sativa Mill.). Erucin is also formed in vivo through the reduction of sulforaphane, an ITC found in broccoli. Erucin displays neuroprotective, antioxidant, and anticancer efficacy in vitro and in vivo by inducing intracellular reactive oxygen species (ROS) production and Nrf2 activaiton.

Orally available, hydrogen sulfide (H2S)-releasing isothiocyanate (ITC) with neuroprotective, antioxidant, and anticancer efficacy via ROS induction and Nrf2 activation.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable