SML2925

MESM

≥98% (HPLC)

• Synonym(s): 5′-(2-Hydroxyphenyl)-1-methylspiro[3H-indole-3,2′(3′H)-[1,3,4]thiadiazol]-2(1H)-one, Manganese-Extracting Small Molecule, VU0028386
• Empirical Formula (Hill Notation): C₁₆H₁₃N₃O₂S
• CAS Number: 360572-26-5
• Molecular Weight: 311.36
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: S1C2(NN=C1c4c(cccc4)O)c3c(cccc3)N(C2=O)C
• InChI: 1S/C16H13N3O2S/c1-19-12-8-4-3-7-11(12)16(15(19)21)18-17-14(22-16)10-6-2-5-9-13(10)20/h2-9,18,20H,1H3
• InChI key: MKCMWNNDSGMHED-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MESM is a cell penetrant and non-toxic selective manganese ionophore that potently facilitates of manganese export from cells. MESM can be used to rapidly extract and quantify cellular manganese content in a non-lethal and selective MESMER (Manganese-Extracting Small Molecule Estimation Route) assay. MESM does not impacted Fura-2 AM fluorescence.

cell penetrant and non-toxic selective manganese ionophore that potently facilitates of manganese export from cells

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable