SML2899

Humanin Trifluoroacetate

≥95% (HPLC)

• Synonym(s): L-Methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L-?-glutamyl-L-isoleucyl-L-?-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-L-alanine trifluoroacetate, MAPRGFSCLLLLTSEIDLPVKRRA trifluoroacetate, Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
• Empirical Formula (Hill Notation): C₁₁₉H₂₀₄N₃₄O₃₂S₂ · xC₂HF₃O₂
• Molecular Weight: 2687.23 (free base basis)
• NACRES: NA.77
• UNSPSC Code: 12352202
• Assay: ≥95% (HPLC)
• Form: lyophilized powder

Properties

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: lyophilized powder
• color: white to beige
• storage temp.: −20°C

Description

Biochem/physiol Actions

Humanin is 24-amino acid mitochondria-associated peptide that is involved in numerous biological processes including apoptosis, cell survival, substrate metabolism, inflammatory response, and response to stressors such as oxidative stress, ischemia, and starvation. Humanin exhibits protective effects against cellular apoptosis. Apparently it inhibits BAX translocation to the mitochondrial outer membrane.

mitochondria-associated peptide; exhibits protective effects against cellular apoptosis

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable