SML2781

NV-5440

≥98% (HPLC), class I glucose transporters (GLUT1) inhibitor, powder

• Synonym(s): 2-[4-[5-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-2,4-dimethylbenzoyl]-1-piperazinyl]-benzenesulfonamide
• Empirical Formula (Hill Notation): C₃₁H₃₆N₆O₃S
• CAS Number: 2226614-88-4
• Molecular Weight: 572.72
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Product Name: NV-5440, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=C(C=C(C(C)=C1)CN2CCN(CC2)C3=C(C=CC=C3)C#N)C(N4CCN(CC4)C5=CC=CC=C5S(N)(=O)=O)=O
• InChI key: BREWSTIKWAQLCH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NV-5440 is a cell penetrant, potent and selective class I glucose transporters (GLUT1) inhibitor that selectively inhibits mTORC1 pathway in vivo. NV-5440 acts as a potent inhibitor of glycolysis in cells.

cell penetrant, potent and selective GLUT1 inhibitor that selectively inhibits mTORC1 pathway in vivo

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable