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SML2546

GLX351322

≥98% (HPLC)

Synonym(s):

2-[[2-[4-(2-Furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester

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About This Item

Empirical Formula (Hill Notation):
C21H25N3O5S
CAS Number:
835598-94-2
Molecular Weight:
431.51
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD05123600
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)SC4=C1CCC4)OCC

InChI key

KEVHLTCEMHIJTQ-UHFFFAOYSA-N

Biochem/physiol Actions

GLX351322 is a potent and selective inhibitor of NOX4 (NADPH oxidase 4). GLX351322 prevents ROS generation and cellular death, improves pancreatic beta cell function in high-fat diet fed C57Bl/6 mice.
potent and selective inhibitor of NOX4 (NADPH oxidase 4)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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