SML0115

MDL 11939

≥98% (HPLC)

• Synonym(s): α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol, Glemanserin, MDL11939
• Empirical Formula (Hill Notation): C₂₀H₂₅NO
• CAS Number: 107703-78-6
• Molecular Weight: 295.42
• NACRES: NA.77
• PubChem Substance ID: 329825167
• UNSPSC Code: 12352200
• MDL number: MFCD00864701
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥8 mg/mL
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: OC(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3
• InChI: 1S/C21H27NO/c23-21(19-11-5-2-6-12-19)20-13-16-22(17-14-20)15-7-10-18-8-3-1-4-9-18/h1-6,8-9,11-12,20-21,23H,7,10,13-17H2
• InChI key: CTDVLAJTGZQELM-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MDL 11,939 is a potent, selective and orally active 5-HT2 receptor antagonist (ASTAR). K_i values values are in the low nanomolar range for 5-HT2A with over 100-fold selectivity over 5-HT2C receptors and low or no affinity for non-5-HT2 receptors or transporters.

Potent, selective, and orally active 5-HT2 receptor antagonist (ASTAR)

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS09
• signalword: Warning
• hcodes: H400
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable