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SAE0004

Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant

Synonym(s):

KMO

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About This Item

EC Number:
1.14.13.9 (BRENDA, IUBMB)
NACRES:
NA.54
UNSPSC Code:
12352204
Specific activity:
≥3 U/mg
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form

solution

Quality Segment

200

specific activity

≥3 U/mg

mol wt

50,712 Da

shipped in

dry ice

storage temp.

−70°C

General description

Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan metabolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein.

Other Notes

1 unit will oxidize L-kynurenine at 1 mol/min at pH 7.0, 25°C.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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