SAB4200673

Monoclonal Anti-α-Amylase 1A antibody produced in mouse

clone AMY-7, purified from hybridoma cell culture

• Synonym(s): AMY1, AMY1A, alpha 1A (salivary), amylase
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: AMY-7, monoclonal
• form: buffered aqueous solution
• mol wt: ~58 kDa
• species reactivity: human, rat, mouse
• concentration: ~1 mg/mL
• technique(s): immunoblotting: 0.25-0.5 μg/mL using rat pancreas tissue extracts.; immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human pancreas sections.
• isotype: IgG1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... AMY1A(276) ; mouse ... Amy1(11722) ; rat ... Amy1a(24203)

Description

General description

Monoclonal Anti- α-Amylase 1A (mouse IgG1 isotype) is derived from the hybridoma AMY-7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with an N-terminal His-tagged recombinant human α. α-Amylase 1A, also known as AMY1A belongs to the α-Amylase family. AMY1A is a secreted digestive enzyme produced by the salivary glands and pancreas.

Immunogen

N-terminal His-tagged recombinant human α-Amylase 1A.

Application

Monoclonal Anti-α-Amylase 1A antibody has been used in immunoblotting, immunohistochemistry.

Biochem/physiol Actions

α-Amylase 1A cleaves the glycosidic linkages in starch molecules to produce smaller saccharides such as maltotriose, maltose, and small amounts of glucose. AMY1A has been identified as an indicator in pancreas and salivary gland diseases, as well as lung cancer, ovarian cancer, plasmacytoma and thyroid adenomas.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable