S9192

Ser-Leu-Ile-Gly-Lys-Val-amide

≥95% (HPLC), Proteinase-activated receptor-2 (PAR2) activator, solid

• Synonym(s): PAR-2 (1-6) Human, PAR2 activating peptide, PAR2-AP, SLIGKV-NH2
• Empirical Formula (Hill Notation): C₂₈H₅₄N₈O₇
• CAS Number: 190383-13-2
• Molecular Weight: 614.78
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824618
• NACRES: NA.32
• MDL number: MFCD02259590

Properties

• Product Name: Ser-Leu-Ile-Gly-Lys-Val-amide, ≥95% (HPLC), solid
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: solid
• UniProt accession no.: Q9WTL4
• storage temp.: −20°C
• SMILES string: CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O
• InChI: 1S/C28H54N8O7/c1-7-17(6)23(36-27(42)20(12-15(2)3)34-25(40)18(30)14-37)28(43)32-13-21(38)33-19(10-8-9-11-29)26(41)35-22(16(4)5)24(31)39/h15-20,22-23,37H,7-14,29-30H2,1-6H3,(H2,31,39)(H,32,43)(H,33,38)(H,34,40)(H,35,41)(H,36,42)/t17-,18-,19-,20-,22-,23-/m0/s1
• InChI key: HOWDUIVVWDUEED-WAUHAFJUSA-N
• Gene Information: mouse ... Insrr(23920)

Description

Biochem/physiol Actions

Proteinase-activated receptor-2 (PAR2)-activating peptide.

Proteinase-activated receptor (PAR-2) is a member of proteolytically cleaved receptors. It is activated by a synthetic peptide (SLIGKV), that is exposed after trypsin cleavage of the amino terminus. PAR-2 stimulates an increase in cytosolic Ca²⁺ ion concentration.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Lyophilized from 0.1% TFA in H2O

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)