R0635

Retinyl Acetate-Water Soluble

BioReagent, suitable for cell culture

• Synonym(s): Retinyl acetate, Retinol Acetate, Vitamin A, Retinol acetate, Vitamin A acetate
• Empirical Formula (Hill Notation): C₂₂H₃₂O₂
• CAS Number: 127-47-9
• Molecular Weight: 328.49
• NACRES: NA.75
• UNSPSC Code: 12352205
• Beilstein/REAXYS Number: 1915439
• MDL number: MFCD00019413
• eCl@ss: 34058009
• Form: powder

Properties

• biological source: synthetic (organic)
• Quality Segment: 200
• product line: BioReagent
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white to light yellow
• mp: 57-58 °C
• solubility: H₂O: 400 mg/mL
• storage temp.: −20°C
• SMILES string: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• InChI key: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Description

General description

Retinyl acetate does not exists naturally, but is derived from retinol. It is considered to be more chemically stable than retinol. For this reason it serves as a dietary supplement for vitamin A source. Vitamin A is found in food of animal origin especially liver and also present in brightly colored vegetables. Vitamin A is a member of carotene family, which is a key component in plant pigments.

Application

Use to study retinoid regulation of cell transformation; cell differentiation and stem cell development.

Retinyl Acetate-Water Soluble has been used as a component of culture medium for secretory cells of venom gland among different Viperidae snakes. It has also been used in testis chunk culturing.

Biochem/physiol Actions

Retinyl acetate is known to prevent carcinogenic polycyclic hydrocarbon, methylcholanthrene induced morphological transformation.

Packaging

Package size based on retinol acetate content

Preparation Note

With a minimum of 3 mg retinol acetate per gram; balance methyl-β-cyclodextrin.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360D
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)