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P9208

Polymyxin Acylase from Pseudomonas sp.

≥0.1 units/mg solid

Synonym(s):

Peptide N-fatty acylase

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About This Item

CAS Number:
111174-43-7
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
MFCD00286307
Specific activity:
≥0.1 units/mg solid
Biological source:
bacterial (Pseudomonas spp.)
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biological source

bacterial (Pseudomonas spp.)

Quality Segment

200

form

solid

specific activity

≥0.1 units/mg solid

relevant disease(s)

cancer

storage temp.

−20°C

Application

Polymyxin acylase, from Pseudomonas sp., is a N-myristoyl cleaving enzyme that has been used to determine the N-myristoyl peptide sequence and may be useful in cancer research since it has antitumor activity against murine and human tumor cells .

Biochem/physiol Actions

Polymyxin acylase, from Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins. Polymyxin acylase has an affinity for long-chain fatty acyl proteins in human carcinoma cells .

Analysis Note

Crude actone powder;

Other Notes

One unit will hydrolyze 1 μmole of N-octanoyl-5-aminovaleric acid per min at pH 8.0 at 37°C.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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