P9053

Pyridine-2-aldoxime methochloride

• Synonym(s): 2-PAM chloride, Pralidoxime chloride
• Empirical Formula (Hill Notation): C₇H₉N₂O · Cl
• CAS Number: 51-15-0
• Molecular Weight: 172.61
• EC Number: 200-080-9
• MDL number: MFCD00011981
• UNSPSC Code: 12352202
• PubChem Substance ID: 24899005
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 100
• form: solid
• mp: 230 °C (lit.)
• solubility: water: 50 mg/mL, clear, colorless to faintly yellow
• SMILES string: [Cl-].C[n+]1ccccc1\C=N\O
• InChI: 1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H
• InChI key: HIGSLXSBYYMVKI-UHFFFAOYSA-N
• Gene Information: human ... ACHE(43)

Description

Biochem/physiol Actions

The prototypical reactivator of acetylcholinesterase that has been inactivated by organophosphorus insecticides or nerve agents. It is now known that no reactivator is effective against a broad spectrum of organophosphorus agents.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves