P8692

Paromomycin sulfate salt

powder, suitable for plant cell culture, BioReagent

• Empirical Formula (Hill Notation): C₂₃H₄₅N₅O₁₄ · xH₂SO₄
• CAS Number: 1263-89-4
• Molecular Weight: 615.63 (free base basis)
• UNSPSC Code: 10171502
• PubChem Substance ID: 24898967
• NACRES: NA.72
• Beilstein/REAXYS Number: 5715182

Properties

• Product Name: Paromomycin sulfate salt, suitable for plant cell culture, BioReagent
• product line: BioReagent
• Quality Segment: 200
• form: powder
• technique(s): cell culture | plant: suitable
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• application(s): agriculture
• mode of action: protein synthesis | interferes
• SMILES string: O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@]2([H])[C@H](O[C@@]3([H])[C@H](O)[C@H](O[C@]4([H])[C@H](N)[C@@H](O)[C@H](O)[C@H](CN)O4)[C@@H](CO)O3)[C@@H](O)[C@H](N)C[C@@H]2N)[C@@H]1N.C
• InChI: 1S/C23H45N5O14.CH4/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;/h5-23,29-36H,1-4,24-28H2;1H4/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
• InChI key: OYJABWUHUYVDMJ-UDXJMMFXSA-N

Description

General description

Chemical structure: aminoglycoside

Application

Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells.

Biochem/physiol Actions

Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, some protozoan species, and limited antihelminth.
Mode of Action: Inhibits initiation and elongation during protein synthesis.

Packaging

5g,25g

Other Notes

Keep container tightly closed in a dry and well-ventilated place

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable