N8164

NSC727447

≥98% (HPLC)

• Synonym(s): 2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid amide
• Empirical Formula (Hill Notation): C₁₀H₁₄N₂OS
• CAS Number: 40106-12-5
• Molecular Weight: 210.30
• NACRES: NA.77
• PubChem Substance ID: 329818683
• UNSPSC Code: 51111800
• MDL number: MFCD00622214
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: >10 mg/mL
• storage temp.: room temp
• SMILES string: NC(=O)c1c(N)sc2CCCCCc12
• InChI: 1S/C10H14N2OS/c11-9(13)8-6-4-2-1-3-5-7(6)14-10(8)12/h1-5,12H2,(H2,11,13)
• InChI key: LULYZYNTDPUEKK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2.

NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. NSC727447 has little activity against E. coli RNase H, but great selectivity over human Rnase H.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable