M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

≥97% (GC), MAO-A inhibitor, powder

• Synonym(s): Clorgyline
• Empirical Formula (Hill Notation): C₁₃H₁₅Cl₂NO · HCl
• CAS Number: 17780-75-5
• Molecular Weight: 308.63
• NACRES: NA.77
• PubChem Substance ID: 24278179
• UNSPSC Code: 12352116
• EC Number: 241-760-5
• MDL number: MFCD00052012
• Assay: ≥97% (GC)
• Form: powder

Properties

• Product Name: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)
• Quality Segment: 100
• assay: ≥97% (GC)
• form: powder
• solubility: DMSO: 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C
• InChI: 1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H
• InChI key: BBAZDLONIUABKI-UHFFFAOYSA-N
• Gene Information: human ... MAOA(4128) ; rat ... Maoa(29253), Maob(25750)

Description

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

• in MAO-A biochemical assay
• to study its effects on the transit of serotonin (5-HT) in the human placenta explants
• to study its effects on human prostate cancer cells

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves