L5011

Leukotriene D₄

~50 μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%

• Synonym(s): LTD₄
• Empirical Formula (Hill Notation): C₂₅H₄₀N₂O₆S
• CAS Number: 73836-78-9
• Molecular Weight: 496.66
• NACRES: NA.77
• PubChem Substance ID: 24896383
• UNSPSC Code: 51111800
• MDL number: MFCD00036839
• Assay: ≥97%

Properties

• Quality Segment: 200
• assay: ≥97%
• concentration: ~50 μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6)
• shipped in: dry ice
• storage temp.: −70°C
• SMILES string: CCCCC\C=C\C/C=C\C=C\C=C\[C@@H](SC[C@@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O
• InChI: 1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6+,10-9-,12-11+,16-13+/t20-,21+,22-/m1/s1
• InChI key: YEESKJGWJFYOOK-GKWRKXFUSA-N

Description

Biochem/physiol Actions

Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca²⁺ in epithelial cells.

Features and Benefits

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Packaged under argon.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk: WGK 3
• flash_point_f: 49.5 °F
• flash_point_c: 9.7 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter