The stability of a 0.001% solution at 4°C has not been tested. A solution of 100 mg/ml in water is stable for 1 year at -80°C and for 1 month at -20°C. It is recommended to aliquot the stock solutions to avoid repeated freeze-thaw cycles.
K4894
Poloxamer 188
solid
Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lutrol F68
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About This Item
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Quality Segment
agency
USP/NF, meets USP testing specifications
form
solid
mol wt
8.400 g/mol
pH
5.0-7.5(2.5% solution)
application(s)
sample preservation
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
General description
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Poloxamer 188 is a non-ionic amphiphilic copolymer, which has a central chain of hydrophobic polyoxypropylene and a hydrophilic polyoxyethylene at the ends.
Poloxamer 188 is a non-ionic amphiphilic copolymer, which has a central chain of hydrophobic polyoxypropylene and a hydrophilic polyoxyethylene at the ends.
Application
Poloxamer 188 has been used as a supplement in F17 medium for the culture of HEK293-6E cells. It has also been used as a component of flow cytometry (FACS) buffer as a non-ionic detergent that protects cells from hydrodynamic damage.
Biochem/physiol Actions
Legal Information
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This Item | |||
|---|---|---|---|
| description solid | description EMPROVE® EXPERT, (stabilized with 70ppm BHT), Ph. Eur., ChP, JPE, NF | description European Pharmacopoeia (EP) Reference Standard | description - |
| form solid | form solid | form - | form solid |
| application(s) sample preservation | application(s) liquid formulation | application(s) pharmaceutical (small molecule) | application(s) - |
| mol wt 8.400 g/mol | mol wt - | mol wt - | mol wt ~7680-9510 g/mol |
| Quality Level 300 | Quality Level 500 | Quality Level - | Quality Level 200 |
| agency USP/NF, meets USP testing specifications | agency ChP, JPE, NF, Ph. Eur. | agency - | agency - |
| pH 5.0-7.5(2.5% solution) | pH 5-7.5 (20 °C, 10 g/L in H2O) | pH - | pH 5.0-7.5 (100 g/L in H2O), 6.0-7.5 (25 g/L in H2O) |
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Storage Class
11 - Combustible Solids
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How long can a 0,001% solution be stored at 4°C?
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