K3125
Kojic acid
≥98.5% (HPLC), powder, tyrosinase inhibitor
Synonym(s):
2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
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About This Item
Empirical Formula (Hill Notation):
C6H6O4
CAS Number:
Molecular Weight:
142.11
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-922-4
MDL number:
Beilstein/REAXYS Number:
120895
Assay:
≥98.5% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Product Name
Kojic acid,
assay
≥98.5% (HPLC)
Quality Segment
form
powder
mp
152-155 °C (lit.)
SMILES string
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
InChI key
BEJNERDRQOWKJM-UHFFFAOYSA-N
Application
Kojic acid has been used:
- as an inhibitor of tyrosinase in guinea pigs pigmented hyperopic (PH)
- as a reference inhibitor standard for screening tyrosinase inhibition
- as a positive control for inhibition of tyrosinase in B16F10 melanoma cells
Biochem/physiol Actions
Kojic acid is derived from some fungal species such as, Aspergillus, Acetobacter and Penicillium.. It halts melanin synthesis by inhibiting tyrosinase enzyme. It is used in the preparation of skin whitening cosmetics. However, kojic acid usage is minimal in cosmetics, as it induces skin irritation by its unstability and cytotoxic nature during long storage. It is an antioxidant and elicits radioprotective effects on chelating with manganese and zinc.
Tyrosinase inhibitor.
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This Item | |||
|---|---|---|---|
| description - | description analytical standard | description ≥98% (HPLC) | description 97% |
| form powder | form - | form powder | form solid |
| assay ≥98.5% (HPLC) | assay ≥99.0% (HPLC) | assay ≥98% (HPLC) | assay 97% |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| mp 152-155 °C (lit.) | mp 152-155 °C (lit.) | mp - | mp 284-294 °C |
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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