I8000

2-Iodosobenzoic acid

≥98% (TLC)

• Synonym(s): IBA
• Linear Formula: OIC₆H₄CO₂H
• CAS Number: 304-91-6
• Molecular Weight: 264.02
• NACRES: NA.26
• PubChem Substance ID: 24896131
• UNSPSC Code: 12352209
• EC Number: 206-159-4
• MDL number: MFCD00002401
• Beilstein/REAXYS Number: 1939973

Properties

• Product Name: 2-Iodosobenzoic acid,
• assay: ≥98% (TLC)
• Quality Segment: 200
• form: powder
• color: white to off-white
• mp: 230 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: OC(=O)c1ccccc1[I]=O
• InChI: 1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)
• InChI key: IFPHDUVGLXEIOQ-UHFFFAOYSA-N

Description

Application

For cleavage of tryptophanyl peptide bonds.

Biochem/physiol Actions

2-Iodosobenzoic acid (IBA) may be used to study enzyme structure and activity. IBA is used as an oxidant which oxidizes vicinal sulfhydryls to disulfides (cysteine residues) within enzymes leading to their inactivation or conformational changes. IBA is also used to cleave tryptophanyl peptide bonds.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves