I6891
H-7
Synonym(s):
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide
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About This Item
Empirical Formula (Hill Notation):
C14H17N3O2S
CAS Number:
Molecular Weight:
291.37
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5482740
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
mp
114 °C
solubility
ethanol: 20 mg/mL, 1 M HCl: 5 mg/mL
storage temp.
2-8°C
SMILES string
CC1CNCCN1S(=O)(=O)c2cccc3cnccc23
InChI
1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3
InChI key
BDVFVCGFMNCYPV-UHFFFAOYSA-N
Gene Information
human ... CALCRL(10203)
rat ... Calcrl(25029)
Biochem/physiol Actions
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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PloS one, 8(2), e54841-e54841 (2013-02-19)
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Journal of fungi (Basel, Switzerland), 5(3) (2019-07-20)
Despite improvement in the prognosis of HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) patients on antiretroviral therapy (ART), cryptococcal meningitis (CM) still causes 10-15% mortality among HIV-infected patients. The immunological impact of ART on the CD4+ and CD8+ T cell
Global Trade Item Number
| SKU | GTIN |
|---|---|
| I6891-25MG | 04061832434049 |
| I6891-5MG | 04061832434056 |