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Key Documents

I1252

Sigma-Aldrich

DL-Isocitric acid trisodium salt hydrate

≥93%

Synonym(s):

threo-DsLs-Isocitric acid trisodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C6H5Na3O7 · xH2O
CAS Number:
Molecular Weight:
258.07 (anhydrous basis)
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.25
Assay:
≥93%

Assay

≥93%

SMILES string

O.[Na+].[Na+].[Na+].OC(C(CC([O-])=O)C([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.H2O/c7-3(8)1-2(5(10)11)4(9)6(12)13;;;;/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3

InChI key

BPEHKAXIRZOKIS-UHFFFAOYSA-K

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Grant C Bullock et al.
Blood, 116(1), 97-108 (2010-04-22)
Human red cell differentiation requires the action of erythropoietin on committed progenitor cells. In iron deficiency, committed erythroid progenitors lose responsiveness to erythropoietin, resulting in hypoplastic anemia. To address the basis for iron regulation of erythropoiesis, we established primary hematopoietic
Metabolism, gliomas, and IDH1.
Jan Smeitink
The New England journal of medicine, 362(12), 1144-1145 (2010-03-26)
Alexander B Taylor et al.
The Journal of biological chemistry, 283(16), 10872-10880 (2008-02-08)
Mitochondrial NAD(+)-specific isocitrate dehydrogenases (IDHs) are key regulators of flux through biosynthetic and oxidative pathways in response to cellular energy levels. Here we present the first structures of a eukaryotic member of this enzyme family, the allosteric, hetero-octameric, NAD(+)-specific IDH
Christopher Armstrong et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 180(5), 775-783 (2010-01-30)
Hibernation elicits a major reduction in whole-animal O(2) consumption that corresponds with active suppression of liver mitochondrial electron transport capacity at, or downstream of, succinate dehydrogenase (SDH). During arousal from the torpor phase of hibernation this suppression is reversed and
Ho-Ju Fan-Chiang et al.
Journal of AOAC International, 93(3), 956-965 (2010-07-16)
Sugar and nonvolatile acid analyses were conducted on 52 samples of blackberries (Rubus spp), the objective being to develop a compositional database for evaluating authenticity and quality. Brix ranged from 6.88 to 16.83, with a mean of 10.82. Titratable acidity

Protocols

We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.

Chromatograms

application for HPLC

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