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Merck

D5764

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonym(s):

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Linear Formula:
C3H3O10P2Na5
CAS Number:
Molecular Weight:
375.95
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

SMILES string

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

biological source

synthetic

form

powder

impurities

3-phosphoglyceric acid, essentially free

color

white to off-white

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 24.5-32.5% (anhydrous)

storage temp.

−20°C

Quality Level

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem/physiol Actions

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Yueqi Zhao et al.
Science advances, 6(12), eaaw9679-eaaw9679 (2020-03-29)
Rhesus D (RhD) is one of the most important immunogenic antigens on red blood cells (RBCs). However, the supply of RhD-negative blood frequently faces critical shortages in clinical practice, and the positive-to-negative transition of the RhD antigen remains a great
Ida Stangerup et al.
Transfusion, 57(8), 1905-1911 (2017-04-30)
No former studies have examined how blood donation influences physical performance in women, who due to menstruation may have a slower recovery of performance. Therefore, the aim of this study was to clarify how VO VO VO VO
Linda Larsson et al.
Vox sanguinis, 116(1), 60-70 (2020-09-13)
Commercial blood bags are predominantly made of polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP). DEHP is favourable for storage of red blood cells (RBC). Historically, removal of DEHP from blood bags has been linked to unacceptable haemolysis levels. Oncoming
Chiara Crestani et al.
Journal of veterinary internal medicine, 32(3), 1051-1059 (2018-04-11)
Optimal procedure for storage of feline blood is needed. Open-collection systems have been employed in feline medicine, thus limiting the possibility for storage. To evaluate indicators of quality of feline blood stored for 35 days at +4°C in a closed-collection
H Gulliksson et al.
Vox sanguinis, 112(1), 33-39 (2016-12-22)
The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation

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