B5435

BIA 2-093

≥98% (HPLC), solid

• Synonym(s): S-(−)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• Empirical Formula (Hill Notation): C₁₇H₁₆N₂O₃
• CAS Number: 236395-14-5
• Molecular Weight: 296.32
• NACRES: NA.77
• PubChem Substance ID: 24891837
• UNSPSC Code: 12352200
• MDL number: MFCD06798333
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: ~21 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: CC(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c3ccccc13
• InChI: 1S/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1
• InChI key: QIALRBLEEWJACW-INIZCTEOSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ; rat ... Scnn1g(24768)

Description

Biochem/physiol Actions

Blocker of voltage-gated sodium channels; significantly blocks excitatory amino acid (glutamate and aspartate) release.

Blocks voltage-gated sodium channels and excitatory amino acid release.

Safety Information

• pictograms: GHS07
• signalword: Warning
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral