A3160

Acetylsalicylic acid

analytical standard

• Synonym(s): 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Linear Formula: 2-(CH₃CO₂)C₆H₄CO₂H
• CAS Number: 50-78-2
• Molecular Weight: 180.16
• UNSPSC Code: 12352106
• NACRES: NA.21
• PubChem Substance ID: 24890723
• EC Number: 200-064-1
• Beilstein/REAXYS Number: 779271
• MDL number: MFCD00002430

Properties

• grade: analytical standard
• Quality Segment: 200
• form: powder
• packaging: vial of 500 mg
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 134-136 °C (lit.)
• application(s): forensics and toxicology; pharmaceutical; veterinary
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Gene Information: human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)

Description

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

Supplied in amber screw-cap vials

Safety Information

• pictograms: GHS07
• signalword: Warning
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 482.0 °F
• flash_point_c: 250 °C
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• hcodes: H302,H412
• pcodes: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3