A1057

L-Aspartic acid β-(7-amido-4-methylcoumarin)

≥98%, suitable for ligand binding assays

• Synonym(s): L-Aspartic acid β-(4-methyl-7-coumarinylamide), L-Aspartic acid 4-(4-methyl-7-coumarinylamide)
• Empirical Formula (Hill Notation): C₁₄H₁₄N₂O₅
• CAS Number: 133628-73-6
• Molecular Weight: 290.27
• UNSPSC Code: 12352209
• PubChem Substance ID: 24890500
• NACRES: NA.26
• MDL number: MFCD00236804

Properties

• Product Name: L-Aspartic acid β-(7-amido-4-methylcoumarin), fluorescent amino acid
• Quality Segment: 200
• assay: ≥98%
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(NC(=O)C[C@H](N)C(O)=O)ccc12
• InChI: 1S/C14H14N2O5/c1-7-4-13(18)21-11-5-8(2-3-9(7)11)16-12(17)6-10(15)14(19)20/h2-5,10H,6,15H2,1H3,(H,16,17)(H,19,20)/t10-/m0/s1
• InChI key: ARZPQBJTLVVDNP-JTQLQIEISA-N

Description

Biochem/physiol Actions

L-Aspartic acid β-(7-amido-4-methylcoumarin) is used as a fluorogenic substrate for studying the specificity and kinetics of lysosomal glycoasparaginase(s) (aspartylglucosaminidase) and L-asparaginase(s).

L-Aspartic acid-β-7-amido-4-methylcoumarin is sensitive and specific fluorogenic substrate used to assay for lysosomal glycoasparaginase (aspartylglucosaminidase) activity and the diagnosis of aspartylglucosaminuria.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)