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Merck

88596

Fluorescein-O′-acetic acid

BioReagent, suitable for fluorescence, ≥90% (HPCE)

Synonym(s):

FOAA, O′-(Carboxymethyl)fluorescein

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About This Item

Empirical Formula (Hill Notation):
C22H14O7
CAS Number:
Molecular Weight:
390.34
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
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Product Name

Fluorescein-O′-acetic acid, BioReagent, suitable for fluorescence, ≥90% (HPCE)

InChI

1S/C22H14O7/c23-12-5-7-16-18(9-12)29-19-10-13(28-11-20(24)25)6-8-17(19)21(16)14-3-1-2-4-15(14)22(26)27/h1-10H,11H2,(H,24,25)(H,26,27)

SMILES string

OC(=O)COc1ccc2c(OC3=CC(=O)C=CC3=C2c4ccccc4C(O)=O)c1

InChI key

VQKDLLIKXLDPHW-UHFFFAOYSA-N

product line

BioReagent

assay

≥90% (HPCE)

form

powder

fluorescence

λex 455 nm; λem 514 nm in 0.1 M Tris pH 8.0

suitability

suitable for fluorescence

Quality Level

Other Notes

Fluorescent label which reacts with amines after activation to give isomerically homogeneous derivatives

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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H Wang et al.
Analytical biochemistry, 281(1), 15-20 (2000-06-10)
A new amine-reactive derivatizing reagent, N-hydroxysuccinimidyl fluorescein-O-acetate (SIFA), was developed for catecholamine (CA) analysis in liquid chromatography. The reactivity of this reagent with the CAs norepinephrine (NE), epinephrine (E), and dopamine (DA) was investigated in detail. In aqueous methanol containing
Analytica Chimica Acta, 423, 77-77 (2000)

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