If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
87128
Tetracycline
98.0-102.0% (HPLC)
Synonym(s):
Tetracycline HCL, Tetracycline Monohydrochloride
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Product Name
Tetracycline, 98.0-102.0% (HPLC)
InChI key
OFVLGDICTFRJMM-WESIUVDSSA-N
InChI
1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
SMILES string
CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
biological source
synthetic
assay
98.0-102.0% (HPLC)
form
powder or crystals
color
faint yellow to dark yellow
mp
172-174 °C (dec.)
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
protein synthesis | interferes
storage temp.
2-8°C
Quality Level
Gene Information
human ... CYP1A2(1544), TERT(7015)
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Related Categories
1 of 4
This Item | T3258 | T8032 | T3383 |
|---|---|---|---|
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| assay 98.0-102.0% (HPLC) | assay 98.0-102.0% (HPLC) | assay - | assay ≥95% (European Pharmacopoeia HPLC assay) |
| form powder or crystals | form powder or crystals | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
Biochem/physiol Actions
Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.
Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.
General description
Other Notes
Packaging
related product
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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How to prepare stock solutions for item 87128-25G, Tetracycline?
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Tetracycline is soluble in methanol, giving a clear solution at up to 30 mg/ml. It is practically insoluble in chloroform and ether, very slightly soluble in water, slightly soluble in alcohol, very soluble in dilute hydrochloric acid and alkali hydroxide solutions.
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devo fare lo stock della tetraciclina. come e in cosa la devo diluire?
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This product is soluble in methanol or ethanol, giving a completely clear solution at up to 30 mg/ml. The stability of this material in solution is pH-dependent. Stock solutions prepared in ethanol are estimated to be stable for 1-3 months when aliquoted and stored at -20°C. Please see the link below to review the product datasheet for T3258, an identical tetracycline product of another brand. The information provided applies to both products.
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/406/734/t3258dat.pdfHelpful?
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