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Merck

79470

D(+)-2-Phosphoglyceric acid sodium salt hydrate

≥75% (calc. on dry substance, enzymatic)

Synonym(s):

D-Glycerate 2-phosphate sodium salt, Sodium D-2-phosphoglycerate hydrate

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About This Item

Empirical Formula (Hill Notation):
C3H7O7P · xNa+ · yH2O
CAS Number:
Molecular Weight:
186.06 (anhydrous free acid basis)
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.26
Assay:
≥75% (calc. on dry substance, enzymatic)
Form:
powder
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Quality Segment

assay

≥75% (calc. on dry substance, enzymatic)

form

powder

impurities

≤1% Pi, ≤35% water

storage temp.

−20°C

SMILES string

O=C(O)[C@@H](CO)OP(O)(O)=O.C.C

InChI key

PXJAQZYAJDMQJH-YBBRRFGFSA-N

Biochem/physiol Actions

Enantiomerically pure metabolite of glycolysis/gluconeogenesis and also substrate for a number of important enzymes in central metabolism like enolase and phosphoglycerate mutase.
The enzyme enolase is responsible for reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). Phosphoglycerate mutase causes reversible isomerization of 3-phosphoglycerate and 2-phosphoglycerate in glycolysis and gluconeogenesis.


Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)



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T M Larsen et al.
Biochemistry, 35(14), 4349-4358 (1996-04-09)
The equilibrium mixture of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-enolpyruvate), has been crystallized from solutions of poly(ethylene glycol) (PEG) at pH 8.0. Crystals belong to the space group C2 and have unit cell dimensions a =
Molecular characterization of phosphoglycerate mutase in archaea.
van der Oost J, et al.
FEMS Microbiology Letters, 212, 111-120 (2002)
Jin-Ha Lee et al.
FEMS microbiology letters, 259(2), 240-248 (2006-06-01)
Enolase on the surface of streptococci putatively facilitates pathogenic invasion of the host organisms. The related Leuconostoc mesenteroides 512FMCM is nonpathogenic, but it too has an extracellular enolase. Purified isolates of extracellular dextransucrase from cultures of L. mesenteroides contain minute



Global Trade Item Number

SKUGTIN
PHR1336-1G04061835233687
N1016-1G04061835557851
N0845000-100MG04061833824887
Y000123704061833797372
N084500004061834093114
N1016-5G04061835516155
N1016-25G04061832785691
79470-250MG04061833046524
79470-50MG04061833046531
79470-1G04061826681107