60142

Potassium chloride solution

BioUltra, Molecular Biology, ~1 M in H₂O

• Synonym(s): KCl, potassium chloride
• Linear Formula: KCl
• CAS Number: 7447-40-7
• Molecular Weight: 74.55
• UNSPSC Code: 12352302
• NACRES: NA.26
• PubChem Substance ID: 57651726
• MDL number: MFCD00011360
• Beilstein/REAXYS Number: 1711999
• Grade: Molecular Biology
• Form: liquid (Clear)
• Solubility: water: soluble

Properties

• InChI key: WCUXLLCKKVVCTQ-UHFFFAOYSA-M
• SMILES string: [Cl-].[K+]
• InChI: 1S/ClH.K/h1H;/q;+1/p-1
• grade: Molecular Biology
• product line: BioUltra
• form: liquid (Clear)
• concentration: ~1 M in H₂O
• impurities: DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected, ≤0.001% total nitrogen (N)
• pH: 5.0-8.0 (25 °C, 1 M in H₂O)
• solubility: water: soluble
• density: 1.04 g/mL at 20 °C
• anion traces: sulfate (SO₄^2-): ≤10 mg/kg
• cation traces: Al: ≤1 mg/kg, Ba: ≤1 mg/kg, Bi: ≤1 mg/kg, Ca: ≤5 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, Li: ≤1 mg/kg, Mg: ≤1 mg/kg, Mn: ≤1 mg/kg, Mo: ≤1 mg/kg, Na: ≤20 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.02, λ: 280 nm A_max: 0.01
• Quality Level: 200

Description

General description

Potassium is an intracellular cation with just 2% of total body K⁺ inhabiting the extracellular fluid. The distribution of K⁺ between the intracellular and extracellular space is analyzed by the action of several transport pathways like Na⁺-K⁺-ATPase, the Na⁺-K⁺-2Cl-cotransporter NKCC1, the four KCCs, and a plethora of K⁺ channels. Also, skeletal muscle comprises almost 75% of total body potassium and elicits considerable influence on extracellular K⁺.[1] Potassium chloride is consumed orally to prevent or correct potassium depletion caused by diuretic use or other conditions. It is used as a food supplement and salt substitute.[2]

Application

Potassium chloride solution has been used as a component of:

• multiple annealing and looping based amplification cycles (MALBAC) lysis buffer to digest proteins for single-cell multiomics sequencing[3]
• single-cell tagged reverse transcription (STRT) buffer, and STRT-RT buffer for single-cell RNA-sequencing[4]
• phosphate buffer saline (PBS) to wash transfected cells[5]

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves