52131

2-C-Methyl-D-erythritol 4-phosphate lithium salt

≥98% (TLC)

• Synonym(s): MEP
• Empirical Formula (Hill Notation): C₅H₁₁O₇P · xLi⁺
• CAS Number: 206440-72-4
• Molecular Weight: 214.11 (free acid basis)
• UNSPSC Code: 12352106
• PubChem Substance ID: 329757790
• NACRES: NA.25
• Assay: ≥98% (TLC)

Properties

• Quality Segment: 100
• assay: ≥98% (TLC)
• storage temp.: −20°C
• SMILES string: O=P(O)(O)OC[C@H](O)[C@@](O)(C)CO.C
• InChI: 1S/C5H13O7P/c1-5(8,3-6)4(7)2-12-13(9,10)11/h4,6-8H,2-3H2,1H3,(H2,9,10,11)/t4-,5+/m1/s1
• InChI key: XMWHRVNVKDKBRG-UHNVWZDZSA-N

Description

Application

2-C-Methyl-D-erythritol 4-phosphate (MEP), the product of reductoisomerase IspC and first committed MEP pathway intermediate, is used to study the non-mevalonate MEP pathway for the biosynthesis of isoprenoids. MEP is used as a precursor for the synthesis of 4-diphosphocytidyl-2-C-methyl D-erythritol (CDP-ME), a key intermediate of the non-mevalonate pathway.

Biochem/physiol Actions

Metabolite intermediate specific to the non-mevalonate MEP pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable