44270

trans,trans-Farnesyl pyrophosphate ammonium salt

≥95.0% (HPLC)

• Synonym(s): (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt, Farnesyl diphosphate ammonium salt
• Empirical Formula (Hill Notation): C₁₅H₂₈O₇P₂ · xNH₃
• Molecular Weight: 382.33 (free acid basis)
• NACRES: NA.25
• PubChem Substance ID: 329756482
• UNSPSC Code: 12352212
• Beilstein/REAXYS Number: 2482197
• Assay: ≥95.0% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• form: solid
• storage temp.: −20°C
• SMILES string: N.C\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O
• InChI: 1S/C15H28O7P2.H3N/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18;/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18);1H3/b14-9+,15-11+;
• InChI key: CPYJTMLHKIWGDF-NDHHSALASA-N

Description

Application

Farnesyl diphosphate ammonium salt may be used to study the posttranslational process known as farnesylation that is used to modify important proteins such as the Ras oncogene.

Biochem/physiol Actions

Farnesyl pyrophosphate is a key intermediate in the biosynthesis of more complex sesquiterpenoids, higher terpenoids, and steroids and different biological functions have been discovered for FPP and the corresponding alcohol farnesol. FPP plays an important role in the posttranslational processing of Ras proteins. Mutated forms of Ras are associated with human cancer and are therefore investigated in cancer research.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable