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41525

N,N-Dimethyl-6-propionyl-2-naphthylamine

Name: <I>N,N</I>-Dimethyl-6-propionyl-2-naphthylamine
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Synonym(s):

2-(Dimethylamino)-6-propionylnaphthalene, 6-Propionyl-2-(dimethylamino)naphthalene, Prodan

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₇NO

CAS Number:

70504-01-7

Molecular Weight:

227.30

UNSPSC Code:

12352116

NACRES:

NA.32

PubChem Substance ID:

57650063

MDL number:

MFCD00056615

Beilstein/REAXYS Number:

2723587

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Properties

product line

BioReagent

Quality Segment

100

assay

≥98.0% (HPLC)

form

solid

solubility

DMF: soluble, acetone: soluble, acetonitrile: soluble, methanol: soluble

fluorescence

λ_ex 361 nm; λ_em 498 nm in methanol

suitability

suitable for fluorescence

SMILES string

CCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3

InChI key

MPPQGYCZBNURDG-UHFFFAOYSA-N

Description

Application

N,N-Dimethyl-6-propionyl-2-naphthylamine (Prodan), a membrane surface probe, may be used as a fluorescence probe in non-cell based in vitro assay for the determination of drug-phospholipid complex formation and to study membrane surface properties.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Fluorescence of spectrin-bound Prodan

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Prodan as a membrane surface fluorescence probe: partitioning between water and phospholipid phases.

E K Krasnowska et al.

Biophysical journal, 74(4), 1984-1993 (1998-04-17)

Fluorescence spectral features of 6-propionyl-2-dimethylaminonaphthalene (Prodan) in phospholipid vesicles of different phase states are investigated. Like the spectra of 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), the steady-state excitation and emission spectra of Prodan are sensitive to the polarity of the environment, showing a relevant

Does PRODAN possess an O-TICT excited state? Synthesis and properties of two constrained derivatives.

Renata K Everett et al.

The journal of physical chemistry. A, 114(14), 4946-4950 (2010-03-25)

The synthesis and photophysical properties of 7-(dimethylamino)-3,4-dihydrophenanthren-1(2H)-one (7) and 3-(dimethylamino)-8,9,10,11-tetrahydro-7H-cyclohepta[a]naphthalen-7-one (8) are reported. These compounds possess a cycloalkanone substructure that controls the extent of twisting of the carbonyl group. The six-membered ring in 7 forces the carbonyl group to be

Solvation dynamics of the fluorescent probe PRODAN in heterogeneous environments: contributions from the locally excited and charge-transferred states.

Ramkrishna Adhikary et al.

The journal of physical chemistry. B, 113(35), 11999-12004 (2009-08-28)

The coexistence of different excited states with different properties of the same chromophores could have significant consequences for the accurate characterization of solvation dynamics in a heterogeneous environment, such as a protein. The purpose of this work is to study

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Global Trade Item Number

SKU	GTIN
41525-100MG	04061832531953
41525-25MG	04061832086330