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40166

Sigma-Aldrich

N,N-Dimethyltetradecylamine N-oxide

≥98.0% (NT)

Synonym(s):

Myristyldimethylamine N-oxide, TDAO

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About This Item

Linear Formula:
CH3(CH2)13N(O)(CH3)2
CAS Number:
3332-27-2
Molecular Weight:
257.46
Beilstein:
4245192
EC Number:
222-059-3
MDL number:
MFCD00045674
UNSPSC Code:
12161900
PubChem Substance ID:
329755934
NACRES:
NA.25

Assay

≥98.0% (NT)

form

powder

mol wt

257.46 g/mol

technique(s)

protein purification: suitable
protein quantification: suitable

pH

5-9 (1 % (w/v) in H2O)

conductivity

≤100 μS/cm at 25 °C

solubility

H2O: 1 % (w/v), clear, colorless

absorption

≤0.06 at 280 nm
≤0.08 at 260 nm

SMILES string

CCCCCCCCCCCCCC[N+](C)(C)[O-]

InChI

1S/C16H35NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17(2,3)18/h4-16H2,1-3H3

InChI key

ONHFWHCMZAJCFB-UHFFFAOYSA-N

Signal Word

Danger

Hazard Statements

H302,H315,H318,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Richard A Cone et al.
BMC infectious diseases, 6, 90-90 (2006-06-03)
Microbicides must protect against STD pathogens without causing unacceptable toxic effects. Microbicides based on nonoxynol-9 (N9) and other detergents disrupt sperm, HSV and HIV membranes, and these agents are effective contraceptives. But paradoxically N9 fails to protect women against HIV
F Devínsky et al.
The Journal of pharmacy and pharmacology, 42(11), 790-794 (1990-11-01)
The antimicrobial activity of the homologous series of N,N-dimethylalkylamine oxides (DMAO) was found to be quasi parabolically dependent on alkyl chain length with a maximum at n approximately 15 and n approximately 12 for Staphylococcus aureus and Escherichia coli, respectively.
Matthias Hofacker et al.
The Journal of biological chemistry, 282(6), 3951-3961 (2006-12-08)
The ATP-binding cassette half-transporter Mdl1 from Saccharomyces cerevisiae has been proposed to be involved in the quality control of misassembled respiratory chain complexes by exporting degradation products generated by the m-AAA proteases from the matrix. Direct functional or structural data
J Lauterwein et al.
Biochimica et biophysica acta, 556(2), 244-264 (1979-09-21)
Complexes of melittin with detergents and phospholipids have been characterized by fluorescence, circular dichroism, ultracentrifugation, quasi-elastic light scattering and 1H nuclear magnetic resonance (NMR) experiments. By ultracentrifugation and quasi-elastic light-scattering measurements it is shown that melittin forms stoichiometrically well-defined complexes
Véronique Peyre et al.
Langmuir : the ACS journal of surfaces and colloids, 21(19), 8865-8875 (2005-09-07)
To evaluate the role of hydrophobic and electrostatic or other polar interactions for protein-ligand binding, we studied the interaction of human serum albumin (HSA) and beta-lactoglobulin with various aliphatic (C10-C14) cationic and zwitterionic detergents. We find that cationic detergents, at
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