383R-1

SOX-10 (EP268) Rabbit Monoclonal Primary Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: EP268, monoclonal
• Application: IHC (p)
• Citations: 6

Properties

• biological source: rabbit
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP268, monoclonal
• description: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (383R-14), vial of 0.5 mL concentrate (383R-15), bottle of 1.0 mL predilute (383R-17), vial of 1.0 mL concentrate (383R-16), bottle of 7.0 mL predilute (383R-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• isotype: IgG
• control: melanoma, skin melanocytes
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... SOX10(6663)

Description

General description

Sry-related HMG-BOX gene 10, SOX-10, is a transcription factor involved in neural crest and peripheral nervous system development and acts as a nucleocytoplasmic shuttle protein. SOX-10 is expressed in melanocytic lineages and is a sensitive melanoma marker for conventional, and desmoplastic subtypes. In normal tissues, SOX-10 is expressed in melanocytes and myoepithelial cells.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

SOX-10 Positive Control Slides, Product No. 383S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany