36798

7-(Diethylamino)coumarin-3-carbohydrazide

BioReagent, suitable for fluorescence, ≥95% (HPCE)

• Empirical Formula (Hill Notation): C₁₄H₁₇N₃O₃
• CAS Number: 100343-98-4
• Molecular Weight: 275.30
• UNSPSC Code: 12352125
• NACRES: NA.32
• PubChem Substance ID: 57649662
• MDL number: MFCD00467583
• Beilstein/REAXYS Number: 5574454

Properties

• product line: BioReagent
• Quality Segment: 100
• assay: ≥95% (HPCE)
• solubility: DMF: soluble, acetonitrile: soluble, chloroform: soluble, methanol: soluble
• fluorescence: λ_ex 450 nm; λ_em 468 nm in methanol
• suitability: suitable for fluorescence
• SMILES string: CCN(CC)c1ccc2C=C(C(=O)NN)C(=O)Oc2c1
• InChI: 1S/C14H17N3O3/c1-3-17(4-2)10-6-5-9-7-11(13(18)16-15)14(19)20-12(9)8-10/h5-8H,3-4,15H2,1-2H3,(H,16,18)
• InChI key: LYBMHAINSFEHRL-UHFFFAOYSA-N

Description

General description

7-(Diethylamino)coumarin-3-carbohydrazide is a coumarin-hydrazide reagent typically used as a fluorescent chemical probe for labeling of cellular carbonyls.

Application

7-(Diethylamino)coumarin-3-carbohydrazide is used for derivatization and detection of carboxylic acid and carbonylated molecules such as lipid peroxidation products (LPP) by electrospray ionization-mass spectrometry (ESI-MS) in positive ion mode. It may be used as a fluorescent label for the determination of lipid aldehydes in food products by normal phase liquid chromatography (NPLC) coupled to ESI-MS and fluorescent detector (FLD) and for the derivatization of monoterpene alcohols in urine prior to analysis by high performance liquid chromatography(HPLC) with FLD coupled to ESI-MS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Derivatizing agent for carboxylic acid detection

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves