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Cytidine 5′-diphosphocholine sodium salt hydrate

Name: Cytidine 5&#8242;-diphosphocholine sodium salt hydrate
Brand: SIGMA

≥99.0% (HPLC), synthetic, powder

Synonym(s):

CDP-choline-Na

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₅N₄NaO₁₁P₂ · xH₂O

CAS Number:

33818-15-4

Molecular Weight:

510.31 (anhydrous basis)

NACRES:

NA.51

PubChem Substance ID:

57648419

UNSPSC Code:

41106305

MDL number:

MFCD00150508

Beilstein/REAXYS Number:

4110040

Assay:

≥99.0% (HPLC)

Biological source:

synthetic

Form:

powder

Storage temp.:

2-8°C

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Properties

Product Name

Cytidine 5′-diphosphocholine sodium salt hydrate, ≥99.0% (HPLC)

biological source

synthetic

Quality Segment

100

assay

≥99.0% (HPLC)

form

powder

impurities

≤8% water

storage temp.

2-8°C

SMILES string

[Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O

InChI

1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1

InChI key

YWAFNFGRBBBSPD-MBWJOHGMSA-M

Description

Application

Cytidine 5′-diphosphocholine (CDP-choline) is generated by choline-phosphate cytidylyltransferase EC 2.7.7.15 in support of the synthesis of phosphatidylcholine. CDP-choline is being used in studies of its affects on neurorecovery.

Cytidine 5′-diphosphocholine sodium salt hydrate has been used as a component of the mixture during the ribonucleotide reductase (RNR) assay in mouse primary pancreatic acinar cells.

Biochem/physiol Actions

Cytidine 5′-diphosphocholine (CDP-choline) is an endogenous compound that plays an important role in the synthesis of phospholipids in the cell membrane. It acts as a choline donor for the biosynthesis of acetylcholine and phosphatidylcholine, a neuronal membrane phospholipid. CDP-choline enhances brain metabolism and influences the levels of various neurotransmitters including dopamine, epinephrine, and acetylcholine. It has been studied as a neuroprotectant after cerebral ischemia. CDP-choline is observed to exhibit therapeutic effects against cognitive impairment arising from multiple causes, cerebral vascular diseases, after-head trauma, and Alzheimer′s disease.

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This Item	C0256	C9755	94330
Sigma-Aldrich 30290 Cytidine 5′-diphosphocholine sodium salt hydrate	Sigma-Aldrich C0256 Cytidine 5′-diphosphocholine sodium salt dihydrate	Sigma-Aldrich C9755 Cytidine 5′-diphosphate sodium salt hydrate	Sigma-Aldrich 94330 Uridine 5′-diphosphate disodium salt hydrate
biological source synthetic	biological source yeast	biological source yeast	biological source synthetic
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100
assay ≥99.0% (HPLC)	assay ~98%	assay ≥95%	assay ≥96.0% (HPLC)
form powder	form solid	form powder	form powder
storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
impurities ≤8% water	impurities -	impurities -	impurities ≤15% water

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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