27606

DL-Malic acid

meets analytical specification of FCC, E296, 99-100.5% (alkalimetric)

• Synonym(s): (±)-2-Hydroxysuccinic acid, DL-Hydroxybutanedioic acid
• Linear Formula: HO₂CCH₂CH(OH)CO₂H
• CAS Number: 6915-15-7
• Molecular Weight: 134.09
• UNSPSC Code: 12352106
• NACRES: NA.25
• PubChem Substance ID: 57648231
• EC Number: 230-022-8
• Beilstein/REAXYS Number: 1723539
• MDL number: MFCD00064212
• Assay: 99-100.5% (alkalimetric)
• Form: solid

Properties

• vapor density: 4.6 (vs air)
• Quality Segment: 200
• vapor pressure: <0.1 mmHg ( 20 °C)
• assay: 99-100.5% (alkalimetric)
• form: solid
• optical activity: [α]/D −0.10 to +0.10°
• autoignition temp.: 644 °F
• quality: meets analytical specification of FCC, E296
• technique(s): IR spectroscopy: suitable
• impurities: ≤0.05% maleic acid, ≤0.1% water insoluble matter, ≤1% fumaric acid
• ign. residue: ≤0.1% (as SO₄)
• mp: 129-133 °C, 131-133 °C (lit.)
• solubility: acetone: soluble 17.75 g/ 100 gm at 20 °C, diethyl ether: soluble 0.84 g/100 gm at 20 °C, dioxane: soluble 22.70 g/100 gm at 20 °C, ethanol: soluble 45.53 g/100 gm at 20 °C, methanol: soluble 82.70 g/100 g at 20 °C, water: soluble 55.8 g/100 gm at 20 °C, benzene: insoluble
• cation traces: As: ≤3 mg/kg, Hg: ≤1 mg/kg, Pb: ≤2 mg/kg
• suitability: complies for identity (IR)
• application(s): pharmaceutical (small molecule)
• SMILES string: OC(CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
• InChI key: BJEPYKJPYRNKOW-UHFFFAOYSA-N

Description

Application

DL-Malic acid is an organic acid used for studying the impact on ultrasound pasteurization. It has also been used to culture Pichia membraneafaciens.

Biochem/physiol Actions

Malic acid is a dicarboxylic acid and an important regulatory metabolite. It has been implicated in process of fruit ripening. Malic acid is important for the starch metabolism; low malic acid content results in transient accumulation of starch. Mitochondrial-malate metabolism modulates ADP-glucose pyrophosphorylase activity and redox status of plastids.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 397.4 °F
• flash_point_c: 203 °C
• ppe: dust mask type N95 (US), Eyeshields, Gloves