163M-1

CD163 (MRQ-26) Mouse Monoclonal Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: MRQ-26, monoclonal
• Application: IHC (p)
• Citations: 7

Properties

• biological source: mouse
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: MRQ-26, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (163M-14), vial of 0.5 mL concentrate (163M-15), bottle of 1.0 mL predilute (163M-17), vial of 1.0 mL concentrate (163M-16), bottle of 7.0 mL predilute (163M-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
• isotype: IgG1
• control: inflamed tissue
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic, membranous
• Gene Information: human ... CD163(9332)

Description

General description

CD163, also known as scavenger receptor cysteine-rich type 1 protein M130, is an acute phase-regulated and signal-inducing transmembrane protein found exclusively on cells of monocytic origin. CD163 plays a critical role in macrophage clearance and endocytosis of hemoglobin/haptoglobin complexes. Therefore, CD163 contributes to the anti-inflammatory response and protects tissues from oxidative and inflammatory hemoglobin. Anti-CD163labels cells of monocytic-macrophage lineage, with expression in the bone marrow and histiocytic neoplasms.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

CD163 Positive Control Slides, Product No. 163S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable