02071

Catalase from Corynebacterium glutamicum

solution, deep brown, ≥500000 U/mL

• CAS Number: 9001-05-2
• NACRES: NA.54
• UNSPSC Code: 12352204
• MDL number: MFCD00081483
• EC Number: 1.11.1.6 (BRENDA, IUBMB)
• eCl@ss: 32160410
• Form: solution

Properties

• biological source: bacterial (Corynebacterium glutamicum)
• Quality Segment: 200
• form: solution
• concentration: ≥500000 U/mL
• color: deep brown
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: O(CC)C(=O)c1ccc(cc1)O
• InChI: 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
• InChI key: NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description

General description

Catalase is ubiquitously found in animals, plants, fungi, and humans. It is made up of looped polypeptide chains that are arranged as tetramers or dimers and a core, that contains iron or manganese ions. Catalase can be differentiated into two types such as heme-containing (type I), which possesses an iron-porphyrin cofactor and a non-heme-containing (type II), which possesses a dinuclear manganese active site.

Application

Catalase from Corynebacterium glutamicum has been used to identify and characterize purified bacterial peptide (PPBP) produced from Bacillus thuringiensis. It has also been used to study its inhibition by nitric oxide.

Biochem/physiol Actions

Catalase is an antioxidant enzyme that plays a role in alleviating oxidative stress by the removal of hydrogen peroxide to produce oxygen and water. Lower levels of catalase lead to several age-related disorders including hypertension, anemia, vitiligo, Parkinson′s disease, Alzheimer′s disease, schizophrenia, bipolar disorders, diabetes mellitus, and cancer.

Physical form

contains ~30% glycerol, 10% ethanol

Other Notes

1 U corresponds to the amount of enzyme which decomposes 1 μmol H₂O₂ per minute at pH 7.0 and 25°C

The purity of this product is not determined. It is tested and sold by activity rather than mass.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 105.8 °F - closed cup
• flash_point_c: 41 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter