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110264

Sigma-Aldrich

2-Butanone

ReagentPlus®, ≥99%

Synonym(s):

Ethyl methyl ketone, MEK, Methyl ethyl ketone

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About This Item

Linear Formula:
C2H5COCH3
CAS Number:
Molecular Weight:
72.11
Beilstein:
741880
EC Number:
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.49 (vs air)

Quality Level

vapor pressure

71 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

≥99%

form

liquid

autoignition temp.

960 °F

expl. lim.

10.1 %

refractive index

n20/D 1.379 (lit.)

bp

80 °C (lit.)

mp

−87 °C (lit.)

density

0.805 g/mL at 25 °C (lit.)

SMILES string

CC(CC)=O

InChI

1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

InChI key

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

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General description

2-Butanone, also known as methyl ethyl ketone (MEK), is a commonly used organic solvent. Due to its low boiling point, low viscosity, ability to accommodate high solid concentrations, and wide diluent tolerance, it has wide applications in the polymer industry and as a solvent in adhesives and paints.

Application


  • Lipid and Volatile Profiles of Finnish Oat Batches of Pure Cultivars: Investigates the effects of storage on volatile formation including 2-Butanone in food processing, which is significant for food scientists and researchers looking into food preservation and flavor profiling (Puganen et al., 2024).

  • Changes in Volatile Compounds and Lipid Oxidation in Various Tissues of Nile Tilapia During Ice Storage: Examines the impact of storage on the volatile compound profiles of seafood, including 2-Butanone, valuable for food scientists and technologists working with seafood preservation and quality assessment (Karbsri et al., 2024).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

30.2 °F - closed cup

Flash Point(C)

-1 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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2-Butanone
Hoell D, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2000)
Ionic-liquid-supported organocatalyst: efficient and recyclable ionic-liquid-anchored proline for asymmetric aldol reaction
Miao W and Chan TH
Advanced Synthesis & Catalysis, 348(12-13), 1711-1718 (2006)
"Identification of chemical interferences in aldehyde and ketone determination using dual-wavelength detection"
Analytical Chemistry, 68(19), 3354- 3358 (1996)
S G Carmella et al.
Cancer research, 53(4), 721-724 (1993-02-15)
Metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a potent pulmonary carcinogen, have been quantified in the urine of 11 smokers. They were not detected in nonsmokers' urine. The metabolites, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronide, were detected in quantities of 0.23-1.0 and 0.57-6.5
L B Goldsmith et al.
Contact dermatitis, 19(5), 348-350 (1988-11-01)
Irritant contact dermatitis along with an increased transepidermal water loss can result from exposing the skin to solvents. A study of the interaction of various solvents with human stratum corneum was made using thin-layer chromatography. Comparison of 10 solvents (trichloroethylene

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