SYNPLE-B032

Reagent-cartridge Nosyl Protection

Synple

• Synonym(s): Synple 2
• UNSPSC Code: 12161503
• NACRES: NA.22
• MDL number: MFCD32903606

Properties

• reaction suitability: reaction type: Amine Protection
• SMILES string: [s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
• InChI key: HVPZHRHEHKZOOJ-TYBLODHISA-N

Description

General description

Reagent-cartridge Nosyl Protection is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the Nosyl protection of primary and secondary free amines. The cartridge contains all necessary reagents to perform the protection of alkyl amines.

Scale: up to 0.8 mmol

Compatible substrates: primary alkyl amines, secondary alkyl amines

Cartridge contents:

• Silica supported triethylamine and o-Ns-Cl (for protection)
• Silica supported Trisamine (for purification)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
• Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety – all chemicals are contained in the system, minimizing the user’s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system – simple installation
• Reaction temperatures from 25 °C – 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301 + H331,H312,H314,H335
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk: WGK 3
• pcodes: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3