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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
S6501
Streptomycin sulfate salt
powder
Synonym(s):
2-[(1S,2R,3R,4S,5R,6R)-5-(diaminomethylideneamino)-2-[(2R,3S,4S,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-oxolan-2-yl]oxy-3,4,6-trihydroxy-cyclohexyl]guanidine
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| Pack Size | SKU | Availability | Price |
|---|
About This Item
biological source
Streptomyces griseus
Quality Segment
form
powder
potency
≥720 I.U. per mg
mol wt
calculated mol wt 1457.38
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria
application(s)
advanced drug delivery
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)C=O)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)C=O)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N
InChI
1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1
InChI key
QTENRWWVYAAPBI-YZTFXSNBSA-N
General description
Application
Biochem/physiol Actions
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Preparation Note
Other Notes
Disclaimer
1 of 1
This Item | |||
|---|---|---|---|
| antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria | antibiotic activity spectrum - |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| application(s) advanced drug delivery | application(s) - | application(s) pharmaceutical (small molecule) | application(s) agriculture |
| form powder | form powder | form liquid | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| S6501-1KG | 04061835549627 |
| S6501-50G | 04061835549641 |
| S6501-10KG | 04061833352076 |
| S6501-5G | 04061835516810 |
| S6501-25G | 04061835549634 |
| S6501-100G | 04061835549610 |
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
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How can the potency of Streptomycin sulfate salt powder S6501 be converted from IU/mg to µg/mg?
1 answer-
The International Unit (IU) of Streptomycin is defined as the activity present in 0.001282 mg or 1.282 µg of the International Standard, as referenced in the literature article below.
According to the reported value from the article above, which is not verified in-house, the following formula is applicable:
Potency (IU/mg dry basis) × 1.282 µg/1 IU = Potency (µg/mg)
Helpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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