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Sulfamethoxazole

Name: Sulfamethoxazole
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N¹-(5-Methylisoxazol-3-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₁N₃O₃S

CAS Number:

723-46-6

Molecular Weight:

253.28

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823147

EC Number:

211-963-3

Beilstein/REAXYS Number:

6732984

MDL number:

MFCD00010546

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Properties

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1631001, traceable to Ph. Eur. S2100000

API family

sulfamethoxazole

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Sulfamethoxazole is one of the most effective sulfa drugs used for treating urinary infections in humans.

Application

Sulfamethoxazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by square-wave voltammetry, and visible/UV spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA6910 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Show Differences

1 of 1

This Item	S2100000	1631001	BP314
Supelco PHR1126 Sulfamethoxazole	S2100000 Sulfamethoxazole	USP 1631001 Sulfamethoxazole	BP314 Sulfamethoxazole
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -	technique(s) -
Quality Level 300	Quality Level -	Quality Level -	Quality Level -
grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
storage temp. 2-30°C	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
API family sulfamethoxazole	API family sulfamethoxazole	API family sulfamethoxazole	API family sulfamethoxazole

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pictograms

GHS08,GHS09

signalword

Warning

hcodes

H361fd,H411

pcodes

P202 - P273 - P280 - P308 + P313 - P391 - P405

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Questions

1–2 of 2 Questions

Anonymous

11 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  11 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

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