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Merck

LIGHTOX58

LightOx58

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C26H25NO2
CAS Number:
Molecular Weight:
383.48
UNSPSC Code:
12352101
NACRES:
NA.22
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assay

≥95% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

N1(CCC(c2c1ccc(c2)C#Cc3ccc(cc3)\C=C\C(=O)OC)(C)C)CC#C

InChI

1S/C26H25NO2/c1-5-17-27-18-16-26(2,3)23-19-22(12-14-24(23)27)11-10-20-6-8-21(9-7-20)13-15-25(28)29-4/h1,6-9,12-15,19H,16-18H2,2-4H3/b15-13+

InChI key

NLKZPAVDCYEIPQ-FYWRMAATSA-N

Application

Fluorescence microscopy, click chemistry, fluorescence spectroscopy.

Features and Benefits

LightOx58 is a fluorescent molecule that exhibits solvatochromatic fluorescence emission when excited with UV-A and violet (405 nm) light sources. In the free, unconjugated form LightOx58 can be used as an intracellular lipid droplet stain, and when photoactivated in a cellular environment, causes cell death through the release of reactive oxygen species (ROS). The N-propargyl group can also be utilized for ′click′ chemistry attachment to an azide-substituted molecule. In a non-polar cellular environment, peak emission wavelength is observed at 475 nm. Stock solutions are typically prepared at 10 mM in DMSO or 1 mM in EtOH.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Chemical Equivalency 1ea=1mg

Legal Information

LightOx is a trademark of LightOx Ltd.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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