LIGHTOX23

LightOx^™23

≥95% (HPLC)

• Empirical Formula (Hill Notation): C₂₁H₂₅NO₂
• CAS Number: 2342579-18-2
• Molecular Weight: 323.43
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• assay: ≥95% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: N1(CCC(c2c1ccc(c2)c3ccc(cc3)C(=O)O)(C)C)C(C)C
• InChI: 1S/C21H25NO2/c1-14(2)22-12-11-21(3,4)18-13-17(9-10-19(18)22)15-5-7-16(8-6-15)20(23)24/h5-10,13-14H,11-12H2,1-4H3,(H,23,24)
• InChI key: XRGDMRFRHFGVNK-UHFFFAOYSA-N

Description

Application

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Biochem/physiol Actions

Weak ligand for retinoic acid receptor proteins

Features and Benefits

LightOx23 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a weak ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx23 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Chemical Equivalency 1ea=1mg

Legal Information

LightOx is a trademark of LightOx Ltd.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable