Key Documents

Gluconolactone

Name: Gluconolactone
Brand: SIAL

99.0-101.0%, meets USP testing specifications

Synonym(s):

D-(+)-Gluconic acid δ-lactone, δ-Gluconolactone, 1,2,3,4,5-Pentahydroxycaproic acid δ-lactone, D-(+)-Dextronic acid δ-lactone

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₀O₆

CAS Number:

90-80-2

Molecular Weight:

178.14

UNSPSC Code:

12352201

NACRES:

NA.21

PubChem Substance ID:

24895089

EC Number:

202-016-5

Beilstein/REAXYS Number:

83286

MDL number:

MFCD00006647

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Properties

biological source

corn

Quality Segment

200

agency

USP/NF, meets USP testing specifications

assay

99.0-101.0%

form

crystalline

color

white

mp

160 °C (dec.) (lit.)

solubility

water: soluble

application(s)

pharmaceutical (small molecule)

SMILES string

OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1

InChI key

PHOQVHQSTUBQQK-SQOUGZDYSA-N

Description

General description

Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.

Application

Gluconolactone has been used:

to control the acidification kinetics of natural rubber latex (NRL) suspensions
to study its effects on inhibition and disintegration of collagen fibrils
to prepare alginate hydrogel

Biochem/physiol Actions

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item	1294150	G4750	PHR3656
Sigma-Aldrich G2164 Gluconolactone	USP 1294150 Gluconolactone	Sigma-Aldrich G4750 D-(+)-Gluconic acid δ-lactone	Supelco PHR3656 Gluconolactone
description 99.0-101.0%, meets USP testing specifications	description United States Pharmacopeia (USP) Reference Standard	description ≥99.0% (GC)	description certified reference material, pharmaceutical secondary standard
assay 99.0-101.0%	assay -	assay ≥99.0% (GC)	assay -
biological source corn	biological source -	biological source microbial	biological source -
Quality Level 200	Quality Level -	Quality Level 300	Quality Level 300
solubility water: soluble	solubility -	solubility water: soluble	solubility -
form crystalline	form -	form powder	form -
mp 160 °C (dec.) (lit.)	mp 160 °C (dec.) (lit.)	mp 160 °C (dec.) (lit.)	mp -

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Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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