80457

Trifluoroacetic acid

eluent additive for LC-MS, LiChropur^™, ≥99.0% (GC)

• Synonym(s): TFA
• Linear Formula: CF₃COOH
• CAS Number: 76-05-1
• Molecular Weight: 114.02
• EC Number: 200-929-3
• UNSPSC Code: 41116105
• NACRES: NB.21
• Beilstein/REAXYS Number: 742035
• MDL number: MFCD00004169
• Assay: ≥99.0% (GC)
• Form: liquid

Properties

• vapor density: 3.9 (vs air)
• Quality Segment: 100
• vapor pressure: 97.5 mmHg ( 20 °C)
• product line: LiChropur^™
• assay: ≥99.0% (GC)
• form: liquid
• technique(s): LC/MS: suitable
• impurities: ≤0.05% water, ≤50 mg/kg total sulfur (as SO₄)
• refractive index: n20/D 1.3 (lit.)
• bp: 72.4 °C (lit.)
• mp: −15.4 °C (lit.)
• solubility: water: soluble 10,000 g/L
• density: 1.489 g/mL at 20 °C (lit.)
• anion traces: chloride (Cl^-): ≤50 mg/kg, sulfite (SO₃^2-): ≤10 mg/kg
• cation traces: Ag: ≤0.05 mg/kg, Al: ≤0.1 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.5 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.1 mg/kg, Co: ≤0.05 mg/kg, Cr: ≤0.1 mg/kg, Cu: ≤0.05 mg/kg, Fe: ≤1.0 mg/kg, K: ≤1.0 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤1.0 mg/kg, Mn: ≤0.1 mg/kg, Mo: ≤0.05 mg/kg, NH₄⁺: ≤10 mg/kg, Na: ≤1.0 mg/kg, Ni: ≤0.1 mg/kg, Pb: ≤0.05 mg/kg, Sr: ≤0.05 mg/kg, Tl: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg
• SMILES string: OC(C(F)(F)F)=O
• UV absorption: λ: 260 nm A_max: ≤0.9, λ: 270 nm A_max: ≤0.1, λ: 280 nm A_max: ≤0.08, λ: 290 nm A_max: ≤0.07, λ: 300 nm A_max: ≤0.06, λ: 320 nm A_max: ≤0.05
• suitability: passes test for LC-MS
• InChI: 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: DTQVDTLACAAQTR-UHFFFAOYSA-N

Description

General description

Trifluoroacetic acidis commonly used as a mobile phase additive in liquid chromatography.

Application

Trifluoroacetic acid may be used as a mobile phase additive for the analysis of basic compounds in liquid chromatography.

Be aware that current batches might contain oxidizing impurities and are not suitable for peptide analysis.

Features and Benefits

• Extensive QC testing
• Low levels of inorganic and organic impurities

Packaging

Clear borosilicateglass, high hydrolytic resistance (Type I)

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Codes: H314,H332,H361d,H412
• Precautionary Statements: P202 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1A
• Storage Class: 8B - Non-combustible corrosive hazardous materials
• supp_hazards: EUH071