34039

Marbofloxacin

VETRANAL^®, analytical standard

• Synonym(s): 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid, Zeniquin^®
• Empirical Formula (Hill Notation): C₁₇H₁₉FN₄O₄
• CAS Number: 115550-35-1
• Molecular Weight: 362.36
• NACRES: NA.24
• PubChem Substance ID: 329754775
• UNSPSC Code: 41116107
• MDL number: MFCD00864820

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O
• InChI: 1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
• InChI key: BPFYOAJNDMUVBL-UHFFFAOYSA-N

Description

General description

Marbofloxacin belongs to the group of synthetic fluoroquinolone compounds, widely used as a veterinary anti-bacterial drug. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria.

Application

The analytical standard can be used as follows:

• Surface-enhanced Raman spectroscopy-based determination of marbofloxacin in chicken and duck samples using β-cyclodextrin-modified silver nanoparticles (β-CD-AgNPs)
• Analysis of synovial fluid and plasma samples obtained from dairy cows for marbofloxacin by high-performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS/MS) following ultrafiltration of the samples
• Development of an indirect competitive ELISA (icELISA) method for the combined analysis of marbofloxacin and ofloxacin in raw milk and porcine samples
• Multi-residue analysis of oxolinic acid, flumequine, marbofloxacin, and enrofloxacin in commercial honey samples by micellar liquid chromatography coupled with fluorescence detection
• Simultaneous determination of marbofloxacin and trovafloxacin in sheep plasma samples by HPLC combined with UV detection
• Quantification of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Zeniquin is a registered trademark of Pfizer, Inc.

Safety Information

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• ppe: Gloves