8.03060

N,N-Dimethylaniline

for synthesis

• Synonym(s): N,N-Dimethylaniline, Dimethylaminobenzene
• Linear Formula: C₆H₅N(CH₃)₂
• CAS Number: 121-69-7
• Molecular Weight: 121.18
• UNSPSC Code: 12352116
• EC Index Number: 204-493-5
• NACRES: NA.22
• MDL number: MFCD00008304
• Assay: ≥99% (GC)
• Form: liquid

Properties

• vapor pressure: 0.53 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99% (GC)
• form: liquid
• autoignition temp.: 370 °C (DIN 51794)
• potency: 1120 mg/kg LD₅₀, oral (Rat), 1700 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.2-7 % (v/v)
• pH: 7.4 (20 °C, 1.2 g/L in H₂O)
• bp: 192-195 °C/1013 hPa
• mp: 2.5 °C
• transition temp: flash point 75 °C
• solubility: 1.2 g/L
• density: 0.96 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: N(C)(C)c1ccccc1
• InChI: 1S/C8H11N/c1-9(2)8-6-4-3-5-7-8/h3-7H,1-2H3
• InChI key: JLTDJTHDQAWBAV-UHFFFAOYSA-N

Description

Application

<ul>
<li><strong>Dual Fluorescence Bioimaging:</strong> N,N-Dimethylaniline derivatives to develop NIR-II emissive donor-acceptor-donor fluorophores. These compounds are used for dual fluorescence bioimaging and photothermal therapy applications, illustrating the critical role of N,N-Dimethylaniline in the development of new biomedical imaging agents (Sparks et al., 2024).</li>
<li><strong>Real-Time Monitoring of Biomolecules: </strong>Dimethylaniline is used in the construction of a fluorescent probe for in vivo real-time imaging and inhibition of A and beta;-fibril formation (Chen et al., 2024).</li>
<li><strong><strong>Photoinduced Electron Transfer Studies: </strong></strong>N,N-dimethylaniline is used in the quenching of the S1 state of two polar dyes, coumarin 152a and Nile red (Verma et al., 2024).</li>
</ul>

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.955 - 0.957
Identity (IR): passes test

Safety Information

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H351,H411
• pcodes: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 167.0 °F - closed cup
• flash_point_c: 75 °C - closed cup